Rapid flow cytometric detection of aberrant cytoplasmic localization of nucleophosmin (NPMc) indicating mutant NPM1 gene in acute myeloid leukemia

Leukemia. 2010 Oct;24(10):1813-6. doi: 10.1038/leu.2010.178. Epub 2010 Aug 19.
No abstract available

Publication types

  • Comparative Study
  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amino Acid Sequence
  • Base Sequence
  • Blast Crisis / diagnosis
  • Blast Crisis / genetics
  • Bone Marrow / metabolism
  • Bone Marrow / pathology
  • Case-Control Studies
  • Cytoplasm / metabolism*
  • Cytoplasm / pathology*
  • Flow Cytometry*
  • Humans
  • Leukemia, Myeloid, Acute / diagnosis
  • Leukemia, Myeloid, Acute / genetics*
  • Molecular Sequence Data
  • Multicenter Studies as Topic
  • Mutation / genetics*
  • Nuclear Proteins / genetics*
  • Nucleophosmin
  • Prognosis
  • Protein Transport
  • Sequence Homology, Amino Acid
  • Sequence Homology, Nucleic Acid

Substances

  • NPM1 protein, human
  • Nuclear Proteins
  • Nucleophosmin