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Fertil Steril. 2010 Dec;94(7):2642-6. doi: 10.1016/j.fertnstert.2010.04.079. Epub 2010 Jun 18.

The status of oocyte cryopreservation in the United States.

Author information

1
Department of Obstetrics and Gynecology, Division of Reproductive Endocrinology and Infertility, University of Southern California, Los Angeles, California 90033, USA. rudick@usc.edu

Abstract

OBJECTIVE:

To determine the current status of oocyte cryopreservation across the United States, and the perceived indications for its use.

DESIGN:

Cross-sectional survey of all IVF Centers in the United States.

SETTING:

Telephone and fax based survey of all IVF practice or laboratory directors, conducted March to June of 2009.

PATIENT(S):

None.

INTERVENTION(S):

None.

MAIN OUTCOME MEASURE(S):

Prevalence of oocyte cryopreservation, acceptable indications and age groups, number of oocyte cryopreservation cycles performed and thawed, fertilization and pregnancy rates, number of live births.

RESULT(S):

Of 442 centers contacted, 282 (64%) responded in 49 states. In these centers 143 (51%) programs currently offer oocyte cryopreservation, with a geographic trend toward the western-located clinics. Of all programs, 36% offer oocyte cryopreservation only for cancer patients or as an alternative to embryo cryopreservation after IVF, whereas 64% of programs offer it electively in women of advancing maternal age. For elective indications, 87% of programs accept patients aged 35-37 years, 49% consider age 38-40 years as acceptable, whereas only 26% of programs cryopreserve oocytes beyond age 40 years. Three hundred thirty-seven live births resulting from 857 thawed cycles (39.3% pregnancy rate [PR]) were reported across all centers.

CONCLUSION(S):

Oocyte cryopreservation is offered in more than 50% of ART clinics in the United States. Most programs that perform oocyte cryopreservation for cancer indications offer it for elective delay of childbearing as well. These data suggest a growing acceptance for this technology within our field.

[Indexed for MEDLINE]

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