Send to

Choose Destination
Intensive Care Med. 1991;17(3):149-53.

HM-PAO-SPECT in persistent vegetative state after head injury: prognostic indicator of the likelihood of recovery?

Author information

Neurological Clinic, University of Vienna, Austria.


Management of patients presenting with traumatic persistent vegetative state (PVS) calls for extensive resources. The ability to predict whether or not a patient is likely to recover is a critical issue. In 12 patients with PVS admitted consecutively for early rehabilitation after head injury, pattern of brain activity was measured by 99mTc-hexamethyl-propylenamineoxime (99mTc-HM-PAO) brain SPECT (single photon emission computer tomography). All patients were re-investigated after a mean observation period of 3 years. A global reduction of cortical blood flow was a reliable predictor of poor long-term outcome, but the demonstration of only focal deficits did not reliably indicate a favourable outcome. Brain SPECT may help to improve outcome prediction in patients with traumatic PVS.

[Indexed for MEDLINE]

Supplemental Content

Loading ...
Support Center