Format

Send to

Choose Destination
See comment in PubMed Commons below
J Biol Chem. 1991 Jul 15;266(20):12944-8.

Genetic polymorphism of rat liver gangliosides.

Author information

1
Institut National de la Santé et de la Recherche Medicale, Unité 76, Paris, France.

Abstract

Liver ganglioside patterns of eight rat strains were classified according to two phenotypes: SHR type, characterized by predominance of b-series gangliosides (GD1b, GT1b, GQ1b), and DA type, characterized by predominance of a-series gangliosides (GM1, GD1a). Comparison of ganglioside pattern expressed in the liver of F1 hybrids and backcross F2 hybrids indicated that SHR type is controlled by a single autosomal-dominant gene which probably determines the expression of sialytransferase 2 activity for synthesis of GD3 from GM3.

PMID:
2071580
[Indexed for MEDLINE]
Free full text
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for HighWire
    Loading ...
    Support Center