Patients who meet the American College of Sports Medicine (ACSM) guidelines (ie, ≥150 min per week of moderate or ≥75 min per week of vigorous exercise [Box 1]) should be encouraged to either maintain (eg, if undergoing therapy) or preferably increase exercise levels, by varying the frequency, intensity, type, and time of exercise every 2–3 weeks (Box 2). Resistance training should be recommended to patients once aerobic training is part of habitual activity (Box 3). Patients who do not follow the ACSM guidelines (Box 4) should be recommended to complete an introductory prescription as described (Box 5). If adequately tolerated, the patient can increase the frequency and duration of exercise until more than 150 min per week of moderate exercise is achieved (Box 6). In patients who maintain exercise behaviour that is consistent with ACSM guidelines for more than 12 weeks, resistance training and exercise variation (Box 2) should be added to the prescription (Box 3). Adapted from reference 4.