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Eur J Radiol. 2011 Nov;80(2):292-6. doi: 10.1016/j.ejrad.2010.07.004. Epub 2010 Aug 13.

Prostate cancer: 1.5 T endo-coil dynamic contrast-enhanced MRI and MR spectroscopy--correlation with prostate biopsy and prostatectomy histopathological data.

Author information

1
Department of Diagnostic Radiology, Copenhagen University Hospital at Herlev, Denmark. elcha@heh.regionh.dk

Abstract

PURPOSE:

To investigate diagnostic accuracy of detection of prostate cancer by magnetic resonance: to evaluate the performance of T2WI, DCEMRI and CSI and to correlate the results with biopsy and radical prostatectomy histopathological data.

MATERIALS AND METHODS:

43 patients, scheduled for radical prostatectomy, underwent prostate MR examination. Prostate cancer was identified by transrectal ultrasonographically (TRUS) guided sextant biopsy. MR examination was performed at 1.5 T with an endorectal MR coil. Cancer localisation was performed on sextant-basis--for comparison between TRUS biopsy, MR techniques and histopathological findings on prostatectomy specimens.

RESULTS:

Prostate cancer was identified in all 43 patients by combination of the three MR techniques. The detection of prostate cancer on sextant-basis showed sensitivity and specificity: 50% and 91% for TRUS, 72% and 55% for T2WI, 49% and 69% for DCEMRI, and 46% and 78% for CSI.

CONCLUSION:

T2WI, DCEMRI and CSI in combination can identify prostate cancer. Further development of MR technologies for these MR methods is necessary to improve the detection of the prostate cancer.

PMID:
20708869
DOI:
10.1016/j.ejrad.2010.07.004
[Indexed for MEDLINE]

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