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Mol Cell. 2010 Aug 13;39(3):321-31. doi: 10.1016/j.molcel.2010.07.012.

Gymnastics of molecular chaperones.

Author information

1
Zentrum für Molekulare Biologie der Universität Heidelberg (ZMBH), DKFZ-ZMBH-Allianz, Heidelberg, Germany. m.mayer@zmbh.uni-heidelberg.de

Abstract

Molecular chaperones assist folding processes and conformational changes in many proteins. In order to do so, they progress through complex conformational cycles themselves. In this review, I discuss the diverse conformational dynamics of the ATP-dependent chaperones of the Hsp60, Hsp70, Hsp90, and Hsp100 families.

PMID:
20705236
DOI:
10.1016/j.molcel.2010.07.012
[Indexed for MEDLINE]
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