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Immunol Today. 1991 Mar;12(3):A29-33.

Molecular genetics of antigenic variation.

Author information

1
The Netherlands Cancer Institute, Amsterdam.

Abstract

Antigenic variation is one of the most effective strategies developed by parasites to escape immune destruction. It requires a large wardrobe of surface coats and mechanisms to exchange one coat for an unrelated one. The molecular principles of antigenic variation are now largely known in the bacterial species Borrelia and Neisseria and in the protozoa of the African trypanosome group and these three examples are discussed here by Piet Borst.

PMID:
2069675
DOI:
10.1016/S0167-5699(05)80009-X
[Indexed for MEDLINE]

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