Format

Send to

Choose Destination
See comment in PubMed Commons below
Chem Soc Rev. 2011 Jan;40(1):138-48. doi: 10.1039/b820255a. Epub 2010 Aug 9.

DNA as supramolecular scaffold for functional molecules: progress in DNA nanotechnology.

Author information

1
University of Southampton, School of Chemistry, Highfield, Southampton SO17 1BJ, UK.

Abstract

Oligonucleotides have recently gained increased attraction as a supramolecular scaffold for the design and synthesis of functional molecules on the nanometre scale. This tutorial review focuses on the recent progress in this highly active field of research with an emphasis on covalent modifications of DNA; non-covalent interactions of DNA with molecules such as groove binders or intercalators are not part of this review. Both terminal and internal modifications are covered, and the various points of attachment (nucleobase, sugar moiety or phosphodiester backbone) are compared. Using selected examples of the recent literature, the diversity of the functionalities that have been incorporated into DNA strands is discussed.

PMID:
20694258
DOI:
10.1039/b820255a
[Indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Royal Society of Chemistry
    Loading ...
    Support Center