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Cancer J. 2010 Jul-Aug;16(4):348-53. doi: 10.1097/PPO.0b013e3181eb3358.

Myeloid-derived suppressor cells in human cancer.

Author information

1
Division of Translational Medicine, Department of Internal Medicine, University of South Florida, Tampa, FL, USA.

Abstract

Myeloid-derived suppressor cells are one of the major factors responsible for immune suppression in cancer. They also contribute to limited efficacy of current vaccination strategies. Here, we give an overview of the myeloid-derived suppressor cells field focusing primarily on the studies in cancer patients and current and future therapeutic options targeting these cells.

PMID:
20693846
DOI:
10.1097/PPO.0b013e3181eb3358
[Indexed for MEDLINE]

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