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Bioinformatics. 2010 Sep 15;26(18):2361-2. doi: 10.1093/bioinformatics/btq426. Epub 2010 Aug 6.

RefProtDom: a protein database with improved domain boundaries and homology relationships.

Author information

1
Department of Biological Sciences, University of Maryland Baltimore County, Baltimore, MD 21250, USA. miledywgonzalez@gmail.com

Abstract

RefProtDom provides a set of divergent query domains, originally selected from Pfam, and full-length proteins containing their homologous domains, with diverse architectures, for evaluating pair-wise and iterative sequence similarity searches. Pfam homology and domain boundary annotations in the target library were supplemented using local and semi-global searches, PSI-BLAST searches, and SCOP and CATH classifications.

AVAILABILITY:

RefProtDom is available from http://faculty.virginia.edu/wrpearson/fasta/PUBS/gonzalez09a.

PMID:
20693322
PMCID:
PMC2935417
DOI:
10.1093/bioinformatics/btq426
[Indexed for MEDLINE]
Free PMC Article
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