Selective inducers of the Coh-locus enhance the metabolisms of coumarin- and of quinoline-derivatives but not that of naphthalenes

Adv Exp Med Biol. 1991:283:353-7. doi: 10.1007/978-1-4684-5877-0_46.
No abstract available

MeSH terms

  • Animals
  • Aryl Hydrocarbon Hydroxylases*
  • Coumarins / metabolism
  • Cytochrome P-450 CYP2A6
  • Cytochrome P-450 Enzyme System / biosynthesis
  • Cytochrome P-450 Enzyme System / genetics*
  • Enzyme Induction
  • Male
  • Mice
  • Mice, Inbred Strains
  • Microsomes, Liver / metabolism
  • Mixed Function Oxygenases / biosynthesis
  • Mixed Function Oxygenases / genetics*
  • Molecular Structure
  • Naphthalenes / metabolism
  • Quinolines / metabolism
  • Substrate Specificity

Substances

  • Coumarins
  • Naphthalenes
  • Quinolines
  • Cytochrome P-450 Enzyme System
  • Mixed Function Oxygenases
  • Aryl Hydrocarbon Hydroxylases
  • Cytochrome P-450 CYP2A6