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J Med Microbiol. 2010 Nov;59(Pt 11):1383-6. doi: 10.1099/jmm.0.023010-0. Epub 2010 Aug 5.

Successful treatment of pan-resistant Klebsiella pneumoniae pneumonia and bacteraemia with a combination of high-dose tigecycline and colistin.

Author information

1
UCLA David Geffen School of Medicine, Department of Pathology and Laboratory Medicine, Los Angeles, CA, USA. rhumphries@mednet.ucla.edu

Abstract

The spread of antimicrobial resistance among members of the Enterobacteriaceae is a significant clinical threat. We report the treatment of pan-resistant Klebsiella pneumoniae bacteraemia with combination tigecycline and colistin in a 49-year-old male and review available therapeutic options. Despite a poor prognosis, the patient recovered, but remains colonized with the pan-resistant isolate.

PMID:
20688947
DOI:
10.1099/jmm.0.023010-0
[Indexed for MEDLINE]

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