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J Am Coll Cardiol. 2010 Aug 10;56(7):539-49. doi: 10.1016/j.jacc.2009.12.075.

Cirrhotic cardiomyopathy.

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Department of Clinical Medicine, University Campus Bio-Medico, Via Alvaro del Portillo, Rome, Italy.

Erratum in

  • J Am Coll Cardiol. 2010 Sep 14;56(12):1000. Van Tassel, Benjamin W [corrected to Van Tassell, Benjamin W].


Cirrhotic cardiomyopathy is a clinical syndrome in patients with liver cirrhosis characterized by an abnormal and blunted response to physiologic, pathologic, or pharmacologic stress but normal to increased cardiac output and contractility at rest. As many as 50% of cirrhotic patients undergoing liver transplantation show signs of cardiac dysfunction, and 7% to 21% of deaths after orthotopic liver transplantation result from overt heart failure. In this review, we critically evaluate the existing literature on the pathophysiology and clinical implications of cirrhotic cardiomyopathy.

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