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Cell Stem Cell. 2010 Aug 6;7(2):145-7. doi: 10.1016/j.stem.2010.07.006.

Differential DNA damage response in stem and progenitor cells.

Author information

1
Stanford Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA. jseita@stanford.edu

Abstract

The long lifespan of tissue-specific stem cells suggests that they may respond differently to DNA damage than downstream cells. In this issue of Cell Stem Cell, two groups address this hypothesis by examining DNA damage responses in hematopoietic stem and progenitor cells (Milyavsky et al., 2010; Mohrin et al., 2010).

PMID:
20682442
DOI:
10.1016/j.stem.2010.07.006
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