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BMC Neurosci. 2010 Aug 2;11:90. doi: 10.1186/1471-2202-11-90.

Adult zebrafish as a model organism for behavioural genetics.

Author information

1
CNRS, UPR, Institute of Neurobiology Albert Fessard, Gif-sur-Yvette, France. norton@inaf.cnrs-gif.fr

Abstract

Recent research has demonstrated the suitability of adult zebrafish to model some aspects of complex behaviour. Studies of reward behaviour, learning and memory, aggression, anxiety and sleep strongly suggest that conserved regulatory processes underlie behaviour in zebrafish and mammals. The isolation and molecular analysis of zebrafish behavioural mutants is now starting, allowing the identification of novel behavioural control genes. As a result of this, studies of adult zebrafish are now helping to uncover the genetic pathways and neural circuits that control vertebrate behaviour.

PMID:
20678210
PMCID:
PMC2919542
DOI:
10.1186/1471-2202-11-90
[Indexed for MEDLINE]
Free PMC Article

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