Format

Send to

Choose Destination
See comment in PubMed Commons below
Mol Cell. 2010 Jul 30;39(2):167-9. doi: 10.1016/j.molcel.2010.07.010.

DNA repair has a new FAN1 club.

Author information

1
Samuel Lunenfeld Research Institute, Mount Sinai Hospital, 600 University Avenue, Toronto, ON M5G 1X5, Canada.

Abstract

In recent issues of Molecular Cell, Cell, and Science, Smogorzewska et al. (2010), MacKay et al. (2010), Kratz et al. (2010), and Liu et al. (2010) identify FAN1 as a nuclease that is recruited to sites of interstrand crosslinks by ubiquitylated FANCD2, where it participates in DNA repair. The identification of FAN1 fills a missing link in interstrand crosslink DNA repair.

PMID:
20670886
DOI:
10.1016/j.molcel.2010.07.010
Free full text
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Elsevier Science
    Loading ...
    Support Center