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Neuron. 2010 Jul 29;67(2):308-20. doi: 10.1016/j.neuron.2010.06.019.

Oscillations and filtering networks support flexible routing of information.

Author information

1
UCL Institute of Neurology, Queen Square, London, UK. t.akam@ion.ucl.ac.uk

Abstract

The mammalian brain exhibits profuse interregional connectivity. How information flow is rapidly and flexibly switched among connected areas remains poorly understood. Task-dependent changes in the power and interregion coherence of network oscillations suggest that such oscillations play a role in signal routing. We show that switching one of several convergent pathways from an asynchronous to an oscillatory state allows accurate selective transmission of population-coded information, which can be extracted even when other convergent pathways fire asynchronously at comparable rates. We further show that the band-pass filtering required to perform this information extraction can be implemented in a simple spiking network model with a single feed-forward interneuron layer. This constitutes a mechanism for flexible signal routing in neural circuits, which exploits sparsely synchronized network oscillations and temporal filtering by feed-forward inhibition.

PMID:
20670837
PMCID:
PMC3125699
DOI:
10.1016/j.neuron.2010.06.019
[Indexed for MEDLINE]
Free PMC Article

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