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Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2010 Aug;110(2):201-8. doi: 10.1016/j.tripleo.2010.03.032.

Effects of probiotic Lactobacillus salivarius WB21 on halitosis and oral health: an open-label pilot trial.

Author information

1
Section of General Dentistry, Department of General Dentistry, Fukuoka Dental College, Fukuoka, Japan.

Abstract

OBJECTIVE:

The objective of this study was to evaluate whether oral administration of lactobacilli alters the degree of halitosis and clinical conditions associated with halitosis.

STUDY DESIGN:

Twenty patients with genuine halitosis were given 2.0 x 10(9)Lactobacillus salivarius WB21 and xylitol in tablet form daily. Oral malodor and clinical parameters were evaluated at the same time of day for each patient after 2 and 4 weeks.

RESULTS:

All 20 patients were positive for L. salivarius DNA in their saliva at 2 weeks, although 12 patients were negative for this organism at baseline. Oral malodor parameters significantly decreased at 2 weeks in the subjects with physiologic halitosis. The scores of an organoleptic test and bleeding on probing significantly decreased at 4 weeks in the subjects with oral pathologic halitosis.

CONCLUSIONS:

Oral administration of probiotic lactobacilli primarily improved physiologic halitosis and also showed beneficial effects on bleeding on probing from the periodontal pocket.

PMID:
20659698
DOI:
10.1016/j.tripleo.2010.03.032
[Indexed for MEDLINE]

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