Format

Send to

Choose Destination
See comment in PubMed Commons below
Vision Res. 2011 Apr 13;51(7):613-32. doi: 10.1016/j.visres.2010.07.010. Epub 2010 Jul 18.

Development of the retina and optic pathway.

Author information

1
Neuroscience Research Institute and Department of Psychology, University of California at Santa Barbara, Santa Barbara, CA 93106-5060, USA. breese@psych.ucsb.edu

Abstract

Our understanding of the development of the retina and visual pathways has seen enormous advances during the past 25years. New imaging technologies, coupled with advances in molecular biology, have permitted a fuller appreciation of the histotypical events associated with proliferation, fate determination, migration, differentiation, pathway navigation, target innervation, synaptogenesis and cell death, and in many instances, in understanding the genetic, molecular, cellular and activity-dependent mechanisms underlying those developmental changes. The present review considers those advances associated with the lineal relationships between retinal nerve cells, the production of retinal nerve cell diversity, the migration, patterning and differentiation of different types of retinal nerve cells, the determinants of the decussation pattern at the optic chiasm, the formation of the retinotopic map, and the establishment of ocular domains within the thalamus.

PMID:
20647017
PMCID:
PMC2974959
DOI:
10.1016/j.visres.2010.07.010
[Indexed for MEDLINE]
Free PMC Article
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Elsevier Science Icon for PubMed Central
    Loading ...
    Support Center