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Pharm Biol. 2010 Apr;48(4):422-6. doi: 10.3109/13880200903150435.

Hypolipidemic effect of fucoidan from Laminaria japonica in hyperlipidemic rats.

Author information

1
Department of Oncology, Guangdong Provincial People's Hospital, Guangzhou, China.

Abstract

In this study, we investigated the effect of fucoidan polysaccharide sulfuric acid ester (FPS) from Laminaria japonica Aresch (Laminariaceae) on hyperlipidemic rats. FPS notably reduced the concentration of serum total cholesterol (TC), triglyceride (TG), and low-density lipoprotein cholesterol (LDL-C) of hyperlipidemic rats and increased the concentration of high-density lipoprotein cholesterol (HDL-C) and the activities of lipoprotein lipase (LPL), hepatic lipoprotein (HL), and lecithin cholesterol acyltransferase (LCAT).

PMID:
20645721
DOI:
10.3109/13880200903150435
[Indexed for MEDLINE]

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