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Head Neck. 2011 Apr;33(4):453-7. doi: 10.1002/hed.21462.

Ultrasonographic screening for occult thyroid cancer.

Author information

1
Hong Kong Head and Neck Ear Nose Throat Surgery Centre, Hong Kong, Central Building, Central, Hong Kong. anthonypwyuen@yahoo.com.hk

Abstract

BACKGROUND:

It has been shown that occult thyroid carcinoma can be identified in about 10% of thyroid glands in autopsy. The purpose of this study was to evaluate the prevalence of asymptomatic thyroid carcinoma in the Hong Kong Chinese population by ultrasonographic screening.

METHODS:

Volunteer subjects without symptoms of thyroid disease were recruited for ultrasonographic screening for thyroid cancer. A total of 1140 subjects were recruited in this study.

RESULTS:

Thyroid nodules were found in 45% subjects (511 of 1140); the mean age was 48 years. Ultrasonographic-guided aspiration cytology was performed in 258 subjects. Twenty-six subjects (2.3%) had cytologic findings suspicious of malignancy. Fourteen subjects (1.2%) had pathologic diagnosis of thyroid cancer, including 13 papillary carcinomas and 1 follicular carcinoma.

CONCLUSION:

A high incidence of occult thyroid cancer could be identified on ultrasonographic screening. Subjects could benefit with early diagnosis with either early intervention or close monitoring.

PMID:
20645291
DOI:
10.1002/hed.21462
[Indexed for MEDLINE]

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