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Cardiology. 2010;116(3):183-5. doi: 10.1159/000315551. Epub 2010 Jul 16.

A hybrid approach in the treatment of post-myocardial infarction ventricular septal defect.

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  • 1Department of Cardiothoracic Surgery, New York Presbyterian Hospital-Weill Cornell Medical College, New York 10065, USA.


Development of ventricular septal defect (VSD) is a rare but serious complication of transmural myocardial infarction (MI). The incidence of post-MI VSDs is reduced significantly with thrombolytic therapy, yet mortality remains high. Surgical repair is difficult and can be complicated by a recurrent VSD in some cases. Percutaneous catheter-based closure techniques can be used to treat these patients. This case report demonstrates the successful application of a hybrid approach utilizing initial surgical and subsequent percutaneous techniques for the recurrence in the treatment of a post-MI VSD.

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