Format

Send to

Choose Destination
Cell Host Microbe. 2010 Jul 22;8(1):12-5. doi: 10.1016/j.chom.2010.06.009.

Viral suppressors of RNA-based viral immunity: host targets.

Author information

1
Department of Plant Pathology and Microbiology, University of California, Riverside, CA 92521, USA.

Abstract

RNA-based viral immunity (RVI) operates in fungi, plants, and invertebrates to specifically destroy viral RNAs using the cellular RNA interference machinery. Discovery of diverse viral proteins as suppressors of RNA silencing provides strong validation for the effectiveness of RVI. Here we review recent studies that have revealed new mechanistic insights into plant and insect viral suppressors of RVI or suggested a role for RNA silencing suppression during mammalian viral infection.

PMID:
20638637
PMCID:
PMC2929401
DOI:
10.1016/j.chom.2010.06.009
[Indexed for MEDLINE]
Free PMC Article

Supplemental Content

Full text links

Icon for Elsevier Science Icon for PubMed Central
Loading ...
Support Center