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Vaccine. 2010 Aug 23;28(37):5979-85. doi: 10.1016/j.vaccine.2010.06.110. Epub 2010 Jul 15.

Measles outbreak in Tanzania, 2006-2007.

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Centers for Disease Control and Prevention, Global Immunization Division, Atlanta, GA 30333, USA.


We conducted a measles outbreak investigation in Dar es Salaam, Tanzania. Surveillance data were analyzed; a susceptibility profile developed, and case-control study conducted. The age distribution of cases peaked among those <2, 5-7, and > or =18 years, corresponding to the age distribution of susceptibles. Risk factors included being unvaccinated (aOR=5.7, p<0.01) or having received one dose of vaccine compared to two (aOR=2.4, p=0.01), being younger, and having a less-educated caretaker. Vaccine effectiveness was 88% (one dose) and 96% (two doses). Results highlight the importance of receiving one dose of measles vaccine, and the added benefit of two doses.

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