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J Vet Emerg Crit Care (San Antonio). 2010 Jun;20(3):319-29. doi: 10.1111/j.1476-4431.2010.00542.x.

Potential risks, prognostic indicators, and diagnostic and treatment modalities affecting survival in dogs with presumptive aspiration pneumonia: 125 cases (2005-2008).

Author information

1
Section of Emergency and Critical Care, Department of Veterinary Clinical Sciences, C339 Veterinary Medical Center, College of Veterinary Medicine, University of Minnesota, St Paul, MN 55108-6192, USA.

Abstract

OBJECTIVE:

To evaluate a clinical population of dogs diagnosed with presumptive aspiration pneumonia (AP) and determine diagnostic and treatment modalities contributing to survival.

DESIGN:

Retrospective study.

SETTING:

A university veterinary teaching hospital in an urban setting.

ANIMALS:

One hundred and twenty-five dogs with presumed AP treated from 2005 to 2008.

INTERVENTIONS:

None.

MEASUREMENTS AND MAIN RESULTS:

Dogs with presumptive AP identified by a review of medical records had an overall survival of 81.6% (102/125). Male large-breed dogs (mean 24.9 kg; 82/125) were overrepresented and were more likely to develop AP in this study population. Recent anesthesia had been performed in 16% (20/125), and vomiting was reported in 64% (80/125). The most common radiographic findings were a predominantly alveolar pattern (187/272, [68.8%] total lung lobes) in the right middle lung lobe (80/115, [69.6%]). A mean of 2 lung lobes were involved radiographically, and the relationship between survival and the number of lung lobes affected was statistically significant (P=0.04). Neutrophilia with a left shift was common with no significant change on consecutive daily evaluations. The mean PaO(2) was 77.7 mm Hg (SD, 17.5 mm Hg) (range, 40.7-100 mm Hg) with a median alveolar-arterial gradient of 41.1 mm Hg (range, 8.1-81.8 mm Hg). In this study population, 37.6% (47/125) of dogs had microbial cultures performed and of these, 76.6% (36/47) were positive for growth; Escherichia coli (38.8%), Mycoplasma spp. (21.3%), Pasturella spp. (19.1%), and Staphylococcus spp. (17%) were the most common isolates in either single or multiagent infections. No treatment modality was statistically associated with increased survival. Colloid therapy was a negative prognostic indicator.

CONCLUSIONS:

In this study the overall prognosis for AP was good. Patients with only 1 affected lung lobe appeared more likely to survive. Supportive treatment modalities are warranted for the hospitalized patient, although no individual treatment method was found to be clearly superior to others.

[Indexed for MEDLINE]

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