Format

Send to

Choose Destination
Future Microbiol. 2010 Jul;5(7):1087-99. doi: 10.2217/fmb.10.68.

Social interactions in the Burkholderia cepacia complex: biofilms and quorum sensing.

Author information

1
Laboratory of Pharmaceutical Microbiology, Ghent University, Harelbekestraat 72, B-9000 Gent, Belgium. tom.coenye@ugent.be

Abstract

Burkholderia cepacia complex bacteria are opportunistic pathogens that cause respiratory tract infections in susceptible patients, mainly people with cystic fibrosis. There is convincing evidence that B. cepacia complex bacteria can form biofilms, not only on abiotic surfaces (e.g., glass and plastics), but also on biotic surfaces such as epithelial cells, leading to the suggestion that biofilm formation plays a key role in persistent infection of cystic fibrosis lungs. This article presents an overview of the molecular mechanisms involved in B. cepacia complex biofilm formation, the increased resistance of sessile B. cepacia complex cells and the role of quorum sensing in B. cepacia complex biofilm formation.

PMID:
20632807
DOI:
10.2217/fmb.10.68
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Atypon
Loading ...
Support Center