[Progress in the development of anti-amyloid drugs for treatment of Alzheimer's disease]

Nihon Yakurigaku Zasshi. 2010 Jul;136(1):15-20. doi: 10.1254/fpj.136.15.
[Article in Japanese]
No abstract available

Publication types

  • Review

MeSH terms

  • Alanine / analogs & derivatives
  • Alzheimer Disease / drug therapy*
  • Alzheimer Disease / etiology
  • Alzheimer Disease / metabolism*
  • Amyloid Precursor Protein Secretases / antagonists & inhibitors*
  • Amyloid beta-Peptides / metabolism*
  • Amyloid beta-Protein Precursor / metabolism
  • Aspartic Acid Endopeptidases / antagonists & inhibitors
  • Azepines
  • Drug Design*
  • Enzyme Inhibitors*
  • Flurbiprofen
  • Humans
  • Taurine / analogs & derivatives

Substances

  • Amyloid beta-Peptides
  • Amyloid beta-Protein Precursor
  • Azepines
  • Enzyme Inhibitors
  • N2-((2S)-2-(3,5-difluorophenyl)-2-hydroxyethanoyl)-N1-((7S)-5-methyl-6-oxo-6,7-dihydro-5H-dibenzo(b,d)azepin-7-yl)-L-alaninamide
  • Taurine
  • tarenflurbil
  • Flurbiprofen
  • tramiprosate
  • Amyloid Precursor Protein Secretases
  • Aspartic Acid Endopeptidases
  • BACE1 protein, human
  • Alanine