Format

Send to

Choose Destination
See comment in PubMed Commons below
Chem Commun (Camb). 2010 Sep 7;46(33):6066-8. doi: 10.1039/c0cc01381a. Epub 2010 Jul 12.

Highly efficient chemoenzymatic synthesis of beta1-4-linked galactosides with promiscuous bacterial beta1-4-galactosyltransferases.

Author information

1
Department of Chemistry, University of California, One Shields Avenue, Davis, California 95616, USA.

Abstract

Two bacterial beta1-4-galactosyltransferases, NmLgtB and Hp1-4GalT, exhibit promiscuous and complementary acceptor substrate specificity. They have been used in an efficient one-pot multienzyme system to synthesize LacNAc, lactose, and their derivatives including those containing negatively charged 6-O-sulfated GlcNAc and C2-substituted GlcNAc or Glc, from monosaccharide derivatives and inexpensive Glc-1-P.

PMID:
20625591
PMCID:
PMC3114949
DOI:
10.1039/c0cc01381a
[Indexed for MEDLINE]
Free PMC Article
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Royal Society of Chemistry Icon for PubMed Central
    Loading ...
    Support Center