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Immunity. 2010 Jun 25;32(6):729-31. doi: 10.1016/j.immuni.2010.06.010.

Only the strong survive.

Author information

1
Division of Developmental Immunology, Biocenter, Innsbruck Medical University, Innsbruck, Austria. andreas.villunger@i-med.ac.at

Abstract

Whether apoptosis is relevant for interclonal competition of T cells after antigen encounter has remained uncertain. In this issue of Immunity, Wensveen et al. (2010) establish a critical role for the proapoptotic BH3-only protein Noxa in this selection process.

PMID:
20620937
DOI:
10.1016/j.immuni.2010.06.010
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