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Semin Nephrol. 2010 May;30(3):216-33. doi: 10.1016/j.semnephrol.2010.03.002.

Monocyte and macrophage biology: an overview.

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1
Institute of Clinical Pathology, Medical University of Vienna, Vienna, Austria. andrew.rees@meduniwien.ac.at

Abstract

This review provides an overview of the current understanding of the biology of monocytes and macrophages. It focuses on four rapidly advancing areas that underpin recent conceptual advances, namely: (1) the bone marrow origins of monocytes and macrophages, (2) monocyte heterogeneity, (3) the early inflammatory consequences of tissue injury, and (4) current concepts of macrophage activation and their limitations.

[Indexed for MEDLINE]

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