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Org Biomol Chem. 2010 Sep 7;8(17):3831-46. doi: 10.1039/c005219c. Epub 2010 Jul 8.

Recent advances in transition metal-catalyzed N-atom transfer reactions of azides.

Author information

1
University of Illinois at Chicago, Department of Chemistry, 845 W. Taylor St., Chicago, IL 60607, USA.

Abstract

Transition metal-catalyzed N-atom transfer reactions of azides provide efficient ways to construct new carbon-nitrogen and sulfur-nitrogen bonds. These reactions are inherently green: no additive besides catalyst is needed to form the nitrenoid reactive intermediate, and the by-product of the reaction is environmentally benign N(2) gas. As such, azides can be useful precursors for transition metal-catalyzed N-atom transfer to sulfides, olefins and C-H bonds. These methods offer competitive selectivities and comparable substrate scope as alternative processes to generate metal nitrenoids.

PMID:
20617243
PMCID:
PMC3095841
DOI:
10.1039/c005219c
[Indexed for MEDLINE]
Free PMC Article

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