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Biol Blood Marrow Transplant. 2011 Feb;17(2):259-64. doi: 10.1016/j.bbmt.2010.06.020. Epub 2010 Jul 6.

Treatment of acyclovir-resistant herpes simplex virus with continuous infusion of high-dose acyclovir in hematopoietic cell transplant patients.

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1
Department of Medicine, Stanford University School of Medicine, Stanford, California, USA.

Abstract

Infection because of herpes simplex virus (HSV) that is resistant to acyclovir (ACV) poses treatment challenges in hematopoietic cell transplant (HCT) patients. We present a series of patients with ACV-resistant HSV following HCT who were successfully treated with continuous infusion high-dose ACV after failing standard treatment regimens for ACV-resistant HSV.

PMID:
20615475
DOI:
10.1016/j.bbmt.2010.06.020
[Indexed for MEDLINE]
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