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Curr Opin Crit Care. 2010 Aug;16(4):323-31. doi: 10.1097/MCC.0b013e32833c0957.

Fluids, pH, ions and electrolytes.

Author information

1
Yale University School of Medicine, Department of Surgery, Section of Trauma, Surgical Critical Care and Surgical Emergencies, New Haven, Connecticut, USA.

Abstract

PURPOSE OF REVIEW:

Significant attention has been recently focused on both maintenance fluid and resuscitation fluid use in critical care. Accordingly, a focused review of the properties of crystalloid and colloid fluids, their expected benefits, and potential deleterious side effects is appropriate and timely.

RECENT FINDINGS:

Despite their ubiquitous use, well described side effects, and ability to be titrated to a physiologic endpoint, fluids are rarely considered in a fashion similar to other pharmacologic agents. Understanding their physical and chemical properties allows the clinician to understand, anticipate and deliberately harness their expected impact on acid-base balance. Expanded insights into the pathogenesis of common acid-base disorders may be gleaned from utilizing a physicochemical approach that allows the precise quantification of the ionic species that impact pH.

SUMMARY:

This focused review further enables the clinician to appropriately investigate, modify, and optimize bedside clinical care related to fluid and acid-base management.

PMID:
20613504
DOI:
10.1097/MCC.0b013e32833c0957
[Indexed for MEDLINE]

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