[Ectasing cholangitis and secondary biliary cirrhosis following intra-arterial hepatic chemotherapy. Treatment by liver transplantation]

J Pitre; D Houssin; A Louvel; C Vigouroux; M Gaudric; Y Chapuis

[Ectasing cholangitis and secondary biliary cirrhosis following intra-arterial hepatic chemotherapy. Treatment by liver transplantation]

Gastroenterol Clin Biol. 1991;15(4):350-4.

[Article in French]

Authors

J Pitre¹, D Houssin, A Louvel, C Vigouroux, M Gaudric, Y Chapuis

Affiliation

¹ Clinique Chirurgical, Hôpital Cochin, Paris.

PMID: 2060745

Abstract

A case of ectasing cholangitis, following intra-arterial chemotherapy with discontinuous infusion of fluorouracile, is described. The severe destruction of the intra-hepatic biliary ducts led to the constitution of large cavities in continuity with the biliary tree. These cavities were responsible for images which were mistakenly thought to be metastases. Consequently, secondary biliary cirrhosis developed, requiring orthotopic liver transplantation.

Publication types

Case Reports

MeSH terms

Adenocarcinoma / drug therapy
Adult
Cholangitis, Sclerosing / chemically induced*
Cholangitis, Sclerosing / diagnostic imaging
Cholangitis, Sclerosing / surgery
Female
Fluorouracil / adverse effects*
Fluorouracil / therapeutic use
Humans
Infusions, Intra-Arterial
Liver Cirrhosis, Biliary / chemically induced*
Liver Cirrhosis, Biliary / diagnostic imaging
Liver Cirrhosis, Biliary / surgery
Liver Transplantation / methods*
Sigmoid Neoplasms / drug therapy
Tomography, X-Ray Computed
Ultrasonography

Substances

Fluorouracil