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Cell. 2010 Jul 9;142(1):9-14. doi: 10.1016/j.cell.2010.06.029.

Metabolic networks of longevity.

Author information

  • 1Laboratory for Integrative and Systems Physiology, Ecole Polytechnique Fédérale de Lausanne, Lausanne 1015, Switzerland.

Abstract

Molecular and cellular networks implicated in aging depend on a multitude of proteins that collectively mount adaptive and contingent metabolic responses to environmental challenges. Here, we discuss the intimate links between metabolic regulation and longevity and outline new approaches for analyzing and manipulating such links to promote human health span.

PMID:
20603007
PMCID:
PMC3852811
DOI:
10.1016/j.cell.2010.06.029
[PubMed - indexed for MEDLINE]
Free PMC Article
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