Format

Send to

Choose Destination
See comment in PubMed Commons below
Neurosci Biobehav Rev. 2011 Jan;35(3):498-515. doi: 10.1016/j.neubiorev.2010.06.004. Epub 2010 Jun 23.

The role of mesocorticolimbic dopamine in regulating interactions between drugs of abuse and social behavior.

Author information

1
Department of Psychology and Program in Neuroscience, Florida State University, Tallahassee, FL 32306-1270, USA. young@psy.fsu.edu

Abstract

The use of addictive drugs can have profound short- and long-term consequences on social behaviors. Similarly, social experiences and the presence or absence of social attachments during early development and throughout life can greatly influence drug intake and the susceptibility to drug abuse. The following review details this reciprocal interaction, focusing on common drugs of abuse (e.g., psychostimulants, opiates, alcohol and nicotine) and social behaviors (e.g., maternal, sexual, play, aggressive and bonding behaviors). The neural mechanisms underlying this interaction are discussed, with a particular emphasis on the involvement of the mesocorticolimbic dopamine system.

PMID:
20600286
PMCID:
PMC3578706
DOI:
10.1016/j.neubiorev.2010.06.004
[Indexed for MEDLINE]
Free PMC Article
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Elsevier Science Icon for PubMed Central
    Loading ...
    Support Center