Monte Carlo-based rigid body modelling of large protein complexes against small angle scattering data

Comput Biol Chem. 2010 Jun;34(3):158-64. doi: 10.1016/j.compbiolchem.2010.05.002. Epub 2010 Jun 2.

Abstract

We present a modular, collaborative, open-source architecture for rigid body modelling based upon small angle scattering data, named sas_rigid. It is designed to provide a fast and extensible scripting interface using the easy-to-learn Python programming language. Features include rigid body modelling to result in static structures and three-dimensional probability densities using two different algorithms.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Models, Molecular*
  • Monte Carlo Method
  • Multiprotein Complexes / chemistry*
  • Proteins
  • Scattering, Small Angle*

Substances

  • Multiprotein Complexes
  • Proteins