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BMC Biol. 2010 Jun 25;8:88. doi: 10.1186/1741-7007-8-88.

Altered metabolism in cancer.

Author information

1
Department of Systems Biology, Harvard Medical School, Boston, MA 02215, USA. jlocasal@bidmc.harvard.edu

Abstract

Cancer cells have different metabolic requirements from their normal counterparts. Understanding the consequences of this differential metabolism requires a detailed understanding of glucose metabolism and its relation to energy production in cancer cells. A recent study in BMC Systems Biology by Vasquez et al. developed a mathematical model to assess some features of this altered metabolism. Here, we take a broader look at the regulation of energy metabolism in cancer cells, considering their anabolic as well as catabolic needs. See research article: http://www.biomedcentral.com/1752-0509/4/58/.

PMID:
20598111
PMCID:
PMC2892450
DOI:
10.1186/1741-7007-8-88
[Indexed for MEDLINE]
Free PMC Article

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