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Psychosom Med. 2010 Sep;72(7):608-12. doi: 10.1097/PSY.0b013e3181e9bf15. Epub 2010 Jul 1.

Relationship between vitamin D levels and depressive symptoms in older residents from a national survey population.

Author information

1
Department of Health Service and Population Research, King's College London (Institute of Psychiatry), London, United Kingdom.

Abstract

OBJECTIVE:

To investigate the association between vitamin D deficiency and depressive symptoms in a national community sample of older people. Vitamin D deficiency is common in older people with potential effects on mood.

METHODS:

Data were analyzed from 2070 participants aged ≥65 years who had participated in the 2005 Health Survey for England. Serum 25-hydroxy vitamin D (25(OH)D) levels and depressive symptoms (Geriatric Depression Scale) had been measured. Covariates included age, sex, social class, season of examination, and physical health status.

RESULTS:

Depressive symptoms were associated with clinical vitamin D deficiency (25(OH)D levels <10 ng/mL; present in 9.8%) independent of other covariates but not with broader deficiency states. This association was not modified by season of examination.

CONCLUSION:

Vitamin D deficiency is associated with late-life depression in northern latitudes.

PMID:
20595420
DOI:
10.1097/PSY.0b013e3181e9bf15
[Indexed for MEDLINE]

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