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Diagn Pathol. 2010 Jun 21;5:40. doi: 10.1186/1746-1596-5-40.

A case of mesothelial/monocytic incidental cardiac excrescence and literature review.

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1
Department of Pathology, Xiangya Medical School, Central South University, Changsha, Hunan Province, China. pjo7858@hotmail.com

Abstract

Mesothelial/monocytic incidental cardiac excrescence (MICE) is a rare entity which is an amalgam of mesothelial cells, histiocytes, and fibrin, often found occasionally during cardiac valve replacement. We report a case in a 25-year-old Chinese female with serous mitral stenosis and patent foramen ovale. Routine and immunohistochemical stains and ultrastructure examination revealed the vegetation was predominantly composed of histocytes with scattered mesothelial cells. In fact nodular histiocytic/mesothelial hyperplasia (NHMH) is a similar lesion to MICE. MICE and NHMH could be unified, and NHMH may be a better choice.

PMID:
20565952
PMCID:
PMC2908560
DOI:
10.1186/1746-1596-5-40
[Indexed for MEDLINE]
Free PMC Article
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