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Hypertens Res. 2010 Sep;33(9):922-5. doi: 10.1038/hr.2010.103. Epub 2010 Jun 17.

Brachial-ankle pulse wave velocity predicts all-cause mortality in the general population: findings from the Takashima study, Japan.

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Department of Health Science, Shiga University of Medical Science, Shiga, Japan.


Brachial-ankle pulse wave velocity (baPWV) is a relatively new non-invasive measure of arterial stiffness obtained using an automated system. We assessed the relationship between baPWV and 6.5-year overall mortality from the Takashima cohort study. The baPWV was measured in 2642 participants at baseline. When participants were divided into tertiles, all-cause mortality increased significantly as baPWV increased (P<0.001). Participants in the highest baPWV tertile showed an increased risk of all-cause mortality evidenced by a multivariable adjusted hazard ratio of 6.8 (95% confidence interval: 1.4-32.8) as compared with the lowest tertile. The present study demonstrated that increased baPWV is an independent predictor of all-cause mortality in the Japanese population.

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