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J Clin Microbiol. 2010 Aug;48(8):3012-5. doi: 10.1128/JCM.00768-10. Epub 2010 Jun 16.

Caught in the act: in vivo development of macrolide resistance to Campylobacter jejuni infection.

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1
Vaccine Testing Center, University of Vermont College of Medicine, Department of Medicine, Burlington, VT 05405, USA. janet.lindow@uvm.edu

Abstract

We report the first instance of macrolide resistance developing in vivo following appropriate antibiotic use in a healthy volunteer as a part of a controlled human infection with Campylobacter jejuni. In vivo development of macrolide resistance may be an important contributor to antibiotic resistance in C. jejuni.

PMID:
20554818
PMCID:
PMC2916616
DOI:
10.1128/JCM.00768-10
[Indexed for MEDLINE]
Free PMC Article
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