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Middle East Afr J Ophthalmol. 2010 Jan;17(1):28-37. doi: 10.4103/0974-9233.61214.

Deep anterior lamellar keratoplasty: indications, surgical techniques and complications.

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Department of Ophthalmology, Labbafinejad Medical Center, Director of Cornea and Refractive Surgery Service, Labbafinejad Medical Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.


The concept of lamellar keratoplasty (LK) is not new. However, it had been abandoned and largely replaced by the time-honored technique of penetrating keratoplasty (PK) because LK is technically demanding, time consuming and gives suboptimal visual outcomes due to interface irregularity arising from manual lamellar dissection. Recent improvements in surgical instruments and introduction of new techniques of maximum depth of corneal dissection as well as inherent advantages such as preservation of globe integrity and elimination of endothelial graft rejection have resulted in a re-introduction of LK as an acceptable alternative to conventional PK. This review article describes the indications, different techniques, clinical outcomes and complications of deep anterior LK.


Anwar's Big-bubble Technique; Deep Anterior Lamellar Keratoplasty; Lamellar Keratoplasty; Melles'Technique; Penetrating Keratoplasty

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