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Diagn Microbiol Infect Dis. 2010 Jul;67(3):297-300. doi: 10.1016/j.diagmicrobio.2010.02.015.

In vitro synergistic/additive activity of levofloxacin with meropenem against Stenotrophomonas maltophilia.

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Infectious Disease Research, Ochsner Clinic Foundation, New Orleans, LA 70121, USA.


Synergy testing of levofloxacin and meropenem by Etest and time-kill assay (TKA) was performed against 30 genetically unique clinical Stenotrophomonas maltophilia isolates. Synergy was demonstrated in 18/30 (60%) isolates by Etest and in 13/30 (43%) by TKA; the remaining isolates were indifferent. Methods showed agreement for 25/30 (83%) of isolates.

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