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J Neural Transm (Vienna). 2010 Jul;117(7):855-9. doi: 10.1007/s00702-010-0425-4. Epub 2010 Jun 10.

Transdermal rotigotine for the perioperative management of Parkinson's disease.

Author information

1
Department of Neurology, University Bonn, Sigmund-Freud-Strasse 25, 53105, Bonn, Germany. wuellner@uni-bonn.de

Abstract

Continuous delivery of antiparkinsonian medication during a perioperative period is desirable to avoid 'off'-symptom complications in surgical patients with concomitant Parkinson's disease (PD). Fourteen PD patients undergoing surgery under general anesthesia were switched from oral dopaminergic medication to transdermally delivered 24-h rotigotine (median dose 12 mg/24 h) for the perioperative period. Rotigotine treatment was considered feasible by patients, their anesthesiologists and neurologists with good control of PD symptoms and easy switching and re-switching of PD medication.

PMID:
20535621
PMCID:
PMC2895903
DOI:
10.1007/s00702-010-0425-4
[Indexed for MEDLINE]
Free PMC Article
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