Format

Send to

Choose Destination
See comment in PubMed Commons below
Cogn Behav Neurol. 2010 Jun;23(2):130-4. doi: 10.1097/WNN.0b013e3181df3007.

"Fantastic thinking" in pathologically proven Pick disease.

Author information

  • 1Neurobehavior Unit, Department of Neurology, VA Greater Los Angeles Healthcare System, Los Angeles, CA 90073, USA. skremen@ucla.edu

Abstract

BACKGROUND:

Reports of false beliefs may be a unique feature of behavioral variant frontotemporal dementia (bvFTD) but the nature of these experiences is unclear.

OBJECTIVE:

To report a case of pathologically verified Pick disease in a patient presenting with prominent and recurrent fantasies.

METHODS:

We describe the clinical, neuroradiologic, and neuropathologic findings of a 53-year-old woman presenting with fantasies and meeting Clinical Consensus Criteria for bvFTD.

RESULTS:

Early in her course, she reported interactions with different actors, having torrid affairs with them, and other related fantasies. When confronted with her false beliefs, she admitted that these relationships were imaginary. Autopsy revealed Pick disease with tau-immunoreactive Pick bodies in the frontal and temporal cortices, and in the hippocampi.

CONCLUSIONS:

Fantastic thinking, or vividly experienced imagination, may be a manifestation of bvFTD that is distinct from delusions and confabulations and could be the source of previously reported delusions and confabulations in bvFTD.

PMID:
20535063
PMCID:
PMC3139563
DOI:
10.1097/WNN.0b013e3181df3007
[PubMed - indexed for MEDLINE]
Free PMC Article
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Lippincott Williams & Wilkins Icon for PubMed Central
    Loading ...
    Support Center