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J Int Assoc Physicians AIDS Care (Chic). 2010 Jul-Aug;9(4):203-5. doi: 10.1177/1545109710371131. Epub 2010 Jun 7.

Low-level viremia associated with the use of TaqMan assay.

Author information

1
HIV Community Program, Christiana Care Health System, Wilmington, DE 19899, USA. sszabo@christianacare.org

Abstract

Poor correlation has been reported between the Roche Cobas AmpliPrep/Cobas (TaqMan) HIV-1 TaqMan assay and the Roche Cobas Amplicor HIV-1 Monitor version 1.5 Amplicor assay. We report 8 patients who experienced unexplained detectable viremia, despite exemplary medication adherence, following a change in viral quantification assay from Amplicor to TaqMan in January 2008. All patients were found to have undetectable HIV RNA by branched DNA (bDNA) assay.

PMID:
20530465
DOI:
10.1177/1545109710371131
[Indexed for MEDLINE]

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