Format

Send to

Choose Destination
See comment in PubMed Commons below
BMC Biol. 2010 May 11;8:53. doi: 10.1186/1741-7007-8-53.

Hidden reach of the micromanagers.

Author information

1
Regulus Therapeutics, 1896 Rutherford Road, Carlsbad, CA 92008, USA. plinsley@regulusrx.com

Abstract

Small interfering RNAs can trigger unintended, microRNA-like off-target effects, but the impact of these effects on functional studies has been controversial. A recent study in BMC Genomics shows that microRNA-like effects can predominate among the 'hits' of functional genomics screens.

PMID:
20529236
PMCID:
PMC2867781
DOI:
10.1186/1741-7007-8-53
[Indexed for MEDLINE]
Free PMC Article
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for BioMed Central Icon for PubMed Central
    Loading ...
    Support Center