Format

Send to

Choose Destination
See comment in PubMed Commons below
Mol Nutr Food Res. 2010 Nov;54(11):1677-89. doi: 10.1002/mnfr.200900582.

Food processing increases casein resistance to simulated infant digestion.

Author information

1
INRA, UMR1253 Science et Technologie du Lait et de l'Œuf,Rennes, France. didier.dupont@rennes.inra.fr

Abstract

The objective of this study was to determine whether processing could modify the resistance of casein (CN) to digestion in infants. A range of different dairy matrices was manufactured from raw milk in a pilot plant and subjected to in vitro digestion using an infant gut model. Digestion products were identified using MS and immunochemical techniques. Results obtained showed that CNs were able to resist digestion, particularly κ- and αs(2)-CN. Resistant areas were identified and corresponded to fragments hydrophobic at pH 3.0 (gastric conditions) and/or carrying post-translational modifications (phosphorylation and glycosylation). Milk processing led to differences in peptide patterns and heat treatment of milk tended to increase the number of peptides found in digested samples. This highlights the likely impact of milk processing on the allergenic potential of CNs.

PMID:
20521278
DOI:
10.1002/mnfr.200900582
[Indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Wiley
    Loading ...
    Support Center